Research Archives - Phelan-McDermid Syndrome Foundation

Early Metformin Treatment in a SHANK3 Mouse Model

In a recent preclinical study, researchers at McGill University found that metformin (an FDA-approved treatment for type 2 diabetes) improved behavior…

NNZ-2591 Phase 2 Publication

By Lauren Schmitt, PhDJanuary 12, 2026With Neuren's Phase 3 clinical trial for NNZ-2591 now open for enrollment, the recent publication of…

Why Sharing Clinical Trial Experiences Can Harm Research

By: Lauren Schmitt, PhD, Chief Science Officer, PMSFDate: December 22, 2025 How Families Can Help Protect the Path to New Treatments…

Why Nutrition Matters in Phelan-McDermid Syndrome

Why Nutrition Matters in Phelan-McDermid Syndrome By: Meagan Hutchinson, Science & Research Administrator, Phelan-McDermid Syndrome FoundationDecember 18, 2025Nutrition plays a critical…

Neuren’s Phase 3 NNZ-2591 Trial for Phelan-McDermid Syndrome is Now Active!

Neuren’s Phase 3 NNZ-2591 Trial for Phelan-McDermid Syndrome is Now Active! by: Lauren Schmitt, PhDDate: December 15, 2025The Phelan-McDermid Syndrome Foundation is…

Updates on the PMS Natural History Study

Updates on the PMS Natural History Study By: Lauren Schmitt, PhD, Chief Science Officer, Phelan-McDermid Syndrome FoundationDecember 11, 2025 What is…

Together We Are Mighty: Attending the 2025 NORD Breakthrough Summit

Together We Are Mighty: Attending the 2025 NORD Breakthrough Summit By: Meagan Hutchinson This week, I had the privilege of attending…

Driving Research Breakthroughs

Driving Research Breakthroughs Funding research, treatments, and cures for Phelan-McDermid SyndromeThe Phelan-McDermid Syndrome Foundation is proud to launch Driving Research Breakthroughs,…

SPACES Webinar Series Recap: Understanding Catatonia in Autism

SPACES Webinar Series Recap: Understanding Catatonia in Autism By Meagan HutchinsonPhelan-McDermid Syndrome Foundation proudly co-sponsored the six-part "Supporting People with Autism…